Our department is involved for > 40 years in the field of RID causing intestinal failure (IF).
Former Chair of our Department, Pr Claude Ricour, was a pioneer in developing parenteral nutrition (PN) in pediatrics in the late 70's. He created the first french expert center for home-PN. In the mid 80's we developed together with the surgical department (Pr Yann Revillon) the first intestinal transplantation (ITx) programme in Europe. Finally, in 2004, we have been recognized as the french pediatric reference center for rare intestinal diseases. Two other centers are part of this reference center: Gastroenterology department at Hopital Robert Debré (Chair: Prof J-P Hugot) and the Intestinal Rehabilitation Center for adults at Hopital Beaujon (Chair: Prof F. Joly) where our patients are referred at transition to adulthood. We are now networked in FIMATHO.
Our international contribution in the specific IF field is illustrated by:
- Admission of patients from the European Community as well as from extra-europe countries
- Guidelines for paediatric PN published in 2005 updated 2016
- Promotion of the concept of Intestinal Rehabilitation Center for IF by organizing a close collaboration with the visceral surgery department of Necker and by writing over 200 pubmed referenced original papers and reviews involving the results of the largest cohorts of patients in Europe and even in US.
- Co-publishing in english 2 important text-books (pediatric gastroenterology, intestinal failure) and writing over 50 chapters in text-books in english as well
- Invitation as lecturer to many International Congresses, conferences, symposia and post-graduate courses
Necker-Enfants Malades University Hospital is gathering 40 centers for rare diseases and displays thus all the specialties that may contribute to the management of the patients within the Network. Our gastroenterology-hepatology and nutrition division has a longstanding experience in the management of IF in children, in close collaboration with the paediatric surgery unit (Chair: Pr Sabine Sarnacki). Although the role of transplantation is decreasing worldwide in the management of irreversible IF, our Tx programme has the largest experience in Europe. Several types of Tx (isolated intestine, liver-intestine, modified multivisceral and multivisceral transplantations) are carried out. Liver Tx in the setting of IF may be necessary. This is possible in our network thanks to the liver unit, that is part of our department and chaired by Dr Dominique Oebray. All the paediatric subspecialities implemented at Necker Hospital offer the unique opportunity of close and fruitful interactions, many resources (like intensive care, anesthesiology, pediatric cardiology, imaging, laboratories, hospital pharmacy .... ) being used in common.
Moreover, the Necker campus hosts the IMAGINE Institute that is fully involved in genetics and immunology.